2015-present

2019

Catalytic Cascade Reactions by Radical Relay
Huang, H-M.; Garduño-Castro, M. H.; Morrill, C.; Procter, D. J.
Chem. Soc. Rev., 2019, in press

Enantioselective and regioselective copper-catalyzed borocyanation of 1-aryl-1,3-butadienes
Jia, T.; Smith, M. J.; Pulis, A. P.; Perry, G. J. P.; Procter, D. J.
ACS Catalysis, 2019, in press

Transition metal-free cross-coupling of benzothiophenes and styrenes in a stereoselective synthesis of substituted (E,Z)-1,3-dienes
Šiaučiulis, M.; Ahlsten, N.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed., 2019, in press

The interrupted Pummerer reaction in a sulfoxide-catalyzed oxidative coupling of 2-naphthols
He, Z.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed., 2019, 58, 7813

Pummerer chemistry of benzothiophene S-oxides: Metal-free alkylation and arylation of benzothiophenes
He, Z.; Pulis, A. P.; Perry, G. J. P.; Procter, D. J.
Phosphorus, Sulfur, and Silicon and the Related Elements, DOI: 10.1080/10426507.2019.1602626
• Invited contribution to an ISOCS-28 special issue

Copper-catalyzed borylative multi-component synthesis of quaternary α-amino esters
Yeung, K.; Talbot, F. J. T.; Howell, G. P.; Pulis, A. P.; Procter, D. J.
ACS Catalysis, 2019, 9, 1655
• Highlighted in Synfacts 2019; 15(05): 0571

SmI2-catalyzed cyclization cascades by radical relay
Huang, H-M.; McDouall, J. J. W.; Procter, D. J.
Nature Catalysis, 2019, 2, 211
• Highlighted in Nature Reviews Chemistry click here
**For a Freeview link to the paper click here

2018

Transition Metal-Free Synthesis of C3-Arylated Benzofurans from Benzothiophenes and Phenols
Yang, K.; Pulis, A. P.; Perry, G. J. P.; Procter, D. J.
Org. Lett. 2018, 20, 7498

Samarium(II) folding cascades involving hydrogen
atom transfer for the synthesis of complex polycycles
Plesniak, M. P.; Garduño-Castro, M. H.; Lenz, P.; Just-Baringo, X.; Procter, D. J.
Nature Commun. 2018, 9, 4802
• Highlighted by the Editor
• Highlighted in Synfacts 2019; 15(02): 0154

Reductive Cyclisations of Amidines involving Aminal Radicals
Huang, H-M.; Adams, R. W.; Procter, D. J.
Chem. Commun. 2018, 54, 10160

Regiodivergent copper catalyzed borocyanation of 1,3-dienes
Tao J.; He, Q.; Ruscoe, R. E.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed. 2018 , 57, 11305

Selective electron transfer reduction of urea-type carbonyls
Huang, H-M.; Procter, D. J.
Eur. J. Org. Chem. 2018, accepted article
• Very Important Paper
• Invited contribution to Special Issue “Organic Reaction Mechanisms”
(Guest Editor Professor Peter R. Schreiner).

An interrupted Pummerer/nickel-catalysed cross-coupling sequence
Aukland, M. H.; Talbot, F. J. T.; Fernández-Salas, J. A.; Ball, M.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed. 2018, 57, 9785
• ChemCatChem Hot Topic: C-C Coupling

Synthesis of C2 Substituted Benzothiophenes via an Interrupted Pummerer/[3,3]-Sigmatropic/1,2-Migration Cascade of Benzothiophene S-Oxides
He, Z.; Shrives, H. J.; Fernández-Salas, J. A.; Abengózar, A.; Neufeld, J.; Yang,K.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed. 2018, 57, 5759
• Highlighted in C2位取代苯并噻吩的高效合成 (in Chinese), 22 May 2018

Radical Anions from Urea-type Carbonyls: Radical Cyclizations and Cyclization Cascades
Huang, H-M.; McDouall, J. J. W.; Procter, D. J.
Angew. Chem. Int. Ed. 2018, 57, 4995
• Highlighted in 脲类羰基自由基引发的环化及串联反应 (in Chinese), 23 April 2018
• Highlighted in 巴比妥酸类化合物的环化反应 (in Chinese), 28 April 2018

Biocatalytic conversion of cyclic ketones bearing α-quaternary stereocenters to lactones in an enantioselective radical approach to medium-sized carbocycles
Morrill, C.; Jensen, C.; Just-Baringo, X.; Grogan, G.; Turner, N. J.; Procter, D. J.
Angew. Chem. Int. Ed. 2018, 57, 3692

Dual vicinal functionalisation of heterocycles via an interrupted Pummerer coupling/[3,3]-sigmatropic rearrangement cascade
Šiaučiulis, M.; Sapmaz, S.; Pulis, A. P.; Procter, D. J.
Chem. Sci. 2018, 9, 754
• Highlighted in Synfacts 2018; 14(04): 0368;

2017

Radical heterocyclization and heterocyclization cascades triggered by electron transfer to amide-type carbonyls
Huang, H-M.; Procter, D. J.
Angew. Chem. Int. Ed. 2017, 56, 14262
• Highlighted in 酰胺自由基参与的自由基氮杂环化以及氮杂串联环化反应 (in Chinese), 08 Dec 2017

Radical cascade reactions triggered by single electron transfer
Plesniak, M. P.; Huang, H-M; Procter, D. J.
Nature Rev. Chem. 2017, 1, 0077
• Issue cover

Enantioselective cyclizations and cyclization cascades of samarium ketyl radicals
Kern, N.; Plesniak, M. P.; McDouall, J. J. W.; Procter, D. J.
Nature Chem. 2017, 9, 1198
• Featured in Nature, Interactive Periodic Table
• Highlighted in "In Abstract Ed 4"
• Highlighted in Synfacts 2017; 13(11): 1195;
• 二碘化钐介导的自由基不对称串联环化反应 (in Chinese), 10 Sep 2017
• 化学前沿 | Nature Chemistry:二碘• 化钐介导的自由基不对称环化反应及环化串联反应 (in Chinese), 25 Aug 2017

Enantioselective copper catalysed, direct functionalisation of allenes via allyl copper intermediates
Pulis, A. P.; Yeung, K.; Procter, D. J.
Chem. Sci. 2017, 8, 5240

Selective construction of quaternary stereocentres in radical cyclisation cascades triggered by electron-transfer reduction of amide-type carbonyls
Huang, H. -M.; Bonilla, P.; Procter, D. J.
Org. Biomol. Chem. 2017, 15, 4159
• Invited contribution to themed issue on Polycyclizations in Synthesis and Biosynthesis

Regioselective synthesis of C3 alkylated and arylated benzothiophenes
Shrives, H. J.; Fernández-Salas, J. A.; Hedtke, C.; Pulis, A. P.; Procter, D. J.
Nature Commun. 2017, 8, 14801

Dearomatizing radical cyclizations and cyclization cascades triggered by electron-transfer reduction of amide-type carbonyls
Huang, H. -M.; Procter, D. J.
J. Am. Chem. Soc. 2017, 139, 1661

Reduction of selenoamides to amines using SmI2-H2O
Thurow, S.; Lenardao, E. J.; Just-Baringo, X.; Procter, D. J.
Org. Lett. 2017, 19, 50

Author profile: D. J. Procter
Angew. Chem. Int. Ed. 2017, 56, 5152

2016

SmCp2-mediated cross-couplings of allyl and propargyl ethers with ketoesters and a telescoped approach to cycloheptanols
Plesniak, M. P.; Just-Baringo, X.; Ortu, F.; Mills, D. P.; Procter, D. J.
Chem. Commun. 2016, 52, 13503

Metal-free C–H thioarylation of arenes using sulfoxides : A direct, general diaryl sulfide synthesis
Fernández-Salas, J. A.; Pulis, A. P.; Procter, D. J.
Chem. Commun. 2016, 52, 12364

Selective synthesis of cyclooctanoids by radical cyclization of seven-membered lactones: Neutron diffraction study of the stereoselective deuteration of a chiral organosamarium intermediate
Just-Baringo, X.; Clark, J.; Gutmann, M. J.; Procter, D. J.
Angew. Chem. Int. Ed. 2016, 55, 12499

Enantioselective generation of adjacent stereocenters in a copper-catalyzed three-component coupling of imines, allenes and diboranes
Yeung, K.; Ruscoe, R. E.; Rae, J.; Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed. 2016, 55, 11912
• Hot Paper
• Highlighted in Synfacts 2016; 12(12): 1267
• 铜催化亚胺、联烯和硼试剂的多组分不对称加成反应 (in Chinese), 6 Sep 2016

Radical-radical cyclization cascades of barbiturates triggered by electron-transfer reduction of amide-type carbonyls
Huang, H. -M.; Procter, D. J.
J. Am. Chem. Soc. 2016, 138, 7770
• Highlighted in Radicals in Action: A Festival of Radical Transformations (ACS Select Virtual Issue, March 2017)

Iron-mediated oxidative C-H coupling of arenes and alkenes directed by sulfur: an expedient route to dihydrobenzofurans
Cavanagh, C. W.; M. H. Aukland, Q. Laurent, A. Hennessy, Procter, D. J.
Org. Biomol. Chem. 2016, 14, 5286
• Invited contribution to themed issue on Contemporary Synthetic Chemistry in Drug Discovery

C-H coupling reactions directed by sulfoxides: teaching an old functional group new tricks
Pulis, A. P.; Procter, D. J.
Angew. Chem. Int. Ed. 2016, 55, 9842

Highly selective SmI2-H2O-promoted radical cyclisation of five-membered lactones
Just-Baringo, X.; Morrill, C.; Procter, D. J.
Tetrahedron 2016, 72, 7691
• Invited contribution to Tetrahedron Symposium in Print, "Organic Chemistry - more radical than ever before"

The role of H2O in the electron transfer-activation of substrates using SmI2: insights from DFT
Zhao, X.; Perrin, L.; Procter, D. J.; Maron, L.
Dalton Trans. 2016, 45, 3706

Metal-Free CH-CH-Type Cross-Coupling of Arenes and Alkynes Directed by a Multifunctional Sulfoxide group
Fernández-Salas, J. A.; Eberhart, A. J.; Procter, D. J.
J. Am. Chem. Soc. 2016, 138, 790
• Highlighted in 无金属催化的芳烃和炔的交叉偶联反应 (in Chinese), 28 Jan 2016

Copper-catalyzed borylative cross-coupling of allenes and imines: Selective three-component assembly of branched homoallyl amines
Rae, J.; Yeung, K.; McDouall, J. J. W.; Procter, D. J.
Angew. Chem. Int. Ed. 2016, 55, 1102
• Highlighted in Synfacts 2016; 12(4): 379

Sulfoxide-directed metal-free cross-couplings in the expedient synthesis of benzothiophene-based components of materials
Eberhart, A. J.; Shrives, H.; Zhang, Y.; Carrër, A.; Parry, A. V. S.; Tate, D. J.; Turner, M. L.; Procter, D. J.
Chem. Sci. 2016, 7, 1281

Copper-catalyzed double additions and radical cyclization cascades in the re-engineering of the antibacterial pleuromutilin
Ruscoe, R. E.; Huang, H.; Flitsch, S.; Procter, D. J.
Chem. –Eur. J. 2016, 22, 116

2015

Overcoming synthetic challenges in target synthesis using SmI2: recent advances
Just-Baringo, X.; Yalavac, I.; Procter, D. J.
Organomet. Chem. 2016, 40, 1

Cenp-E inhibitor GSK923295: novel synthetic route and use as a tool to generate aneuploidy
Bennett, A.; Bechi, B.; Tighe, A.; Thompson, S.; Procter, D. J.; Taylor, S. S. Oncotarget. 2015, 6, 20921

MYC Is a Major Determinant of Mitotic Cell Fate
Topham, C.; Tighe, A; Ly, P.; Bennett, A.; Sloss, O.; Nelson, L.; Ridgway, R. A.; Huels, D.; Littler, S.; Schandl, C.; Sun, Y.; Bechi, B.; Procter, D. J.; Sansom, O. J.; Cleveland, D. W.; Taylor, S. S.
Cancer Cell 2015, 28, 129

Iron-mediated C-H Coupling of Arenes and Unactivated Terminal Alkenes Directed by Sulfur
Cavanagh, C. W.; Aukland, M. H.; Hennessy, A.; Procter, D. J.
Chem. Commun. 2015, 51, 9272

Sm(II)-Mediated Electron Transfer to Carboxylic Acid Derivatives: Development of Complexity Generating Cascades
Just-Baringo, X.; Procter, D. J.
Acc. Chem. Res. 2015, 48, 1263
• Invited Account

Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics
Eberhart, A. J.; Shrives, H. J.; Álvarez, E.; Carrër, A.; Zhang, Y.; Procter, D. J.
Chem. –Eur. J. 2015, 21, 7428
• Hot paper
• Cover art
• Cover profile